Proteasome subunit beta type 1 interacts directly with Rheb and regulates the cell cycle in Cashmere goat fetal fibroblasts
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چکیده
منابع مشابه
Characteristics Determination of Rheb Gene and Protein in Raini Cashmere Goat
The aim of the present study was todeterminecharacteristics of Rheb gene and protein in Raini Cashmere goat. Comparative analyses of the nucleotide sequences were performed. Open reading frames (ORFs), theoretical molecular weights of deduced polypeptides, the protein isoelectric point, protein characteristics and three-dimensional structures was predicted using online standard softwares. The f...
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چکیده ندارد.
Jab1 Interacts Directly with HIF-1 and Regulates Its Stability*
Hypoxia-inducible factor-1 (HIF-1) is a master transcription factor that controls transcriptional activation of a number of genes responsive to the low cellular oxygen tension, including vascular endothelial growth factor (VEGF), erythropoietin, and glycolytic enzymes. The stability and activity of HIF-1 are regulated by binding to various proteins such as pVHL, p53, and p300/CBP. Here, using t...
متن کاملDirect Interaction between Ras Homolog Enriched in Brain and FK506 Binding Protein 38 in Cashmere Goat Fetal Fibroblast Cells
Ras homolog enriched in brain (Rheb) and FK506 binding protein 38 (FKBP38) are two important regulatory proteins in the mammalian target of rapamycin (mTOR) pathway. There are contradictory data on the interaction between Rheb and FKBP38 in human cells, but this association has not been examined in cashmere goat cells. To investigate the interaction between Rheb and FKBP38, we overexpressed goa...
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The proteasome is a multisubunit proteolytic enzyme comprising activator complexes bound to the 20 S catalytic core. The functions of the proteasomal activator (PA) 700 in ubiquitin/ATPdependent protein degradation and of the PA28α/β activators in antigen presentation are well defined. However, the function of a third PA, PA28γ , remains elusive. We now show that mitogenactivated protein kinase...
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ژورنال
عنوان ژورنال: Animal Cells and Systems
سال: 2017
ISSN: 1976-8354,2151-2485
DOI: 10.1080/19768354.2017.1371072